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[DOI] [PMC free article] [PubMed] [Google Scholar] [78].Petrou C, Sarigiannis Y, 1 - Peptide synthesis: Methods, trends, and challenges, in: Koutsopoulos S (Ed.) Peptide Applications in Biomedicine, Biotechnology and Bioengineering, Woodhead Publishing
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Loren Pickart isolated it from human plasma in 1973, after noticing that plasma from young donors caused old liver tissue to behave differently
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