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Anyone with a known allergy to glutathione or its components Patients with significant liver or kidney disease Pregnant or breastfeeding individuals People currently undergoing active cancer treatment Patients taking medications that may interact with the infusion A responsible provider will always screen for these factors before recommending treatment

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Paradoxically, however, this mechanism evidently is not especially widespread or effective, as ferroptosis is readily induced in dozens of different cell lines in response to acute administration of system x c − inhibition [18, 27, 66]