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In early May 2026, one nominator clarified that it had meant to withdraw only its nomination of the injectable route of administration
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In vivo studies in EMs rodent models show that THP administration significantly reduces ectopic lesion volume and weight while also normalizing systemic inflammation by lowering serum TNF-α levels and rebalancing epithelial-stromal crosstalk through modulation of epidermal growth factor (EGF) signaling, specifically by downregulating overexpressed EGF receptor (EGFR), phosphoinositide 3-kinase (PI3K), and serine/threonine kinase Akt (Wuputra et al., 2026)
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