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The convergence of AlphaFold-class structural prediction, generative AI design (à la Baker and Chai Discovery), and high-throughput automated synthesis platforms (generate-and-test pipelines now operating at 10,000+ compounds per week at facilities like Recursion Pharmaceuticals' robotic laboratory in Salt Lake City) means that the pipeline from identified inflammatory target to characterized peptide therapeutic will compress from decades to years

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Two timing strategies dominate the research: Morning fasted: Administering IGF-1 LR3 in a fasted state maximizes receptor sensitivity