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NMN-administered mice show enhancement of energy metabolism and higher physical activity during the dark time Because NMN-administered mice showed higher food intake but lower body weight compared to control mice during the process of aging, we measured oxygen consumption, energy expenditure, and respiratory quotient at the 6- and 12-month time points for control, 100 and 300 mg/kg/day NMN-administered mice (Figures 3A–E)
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