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The importance of this group of proteins may be exemplified by the Nobel prizes awarded for the study of various aspects of an important family of 901 (in human) integral membrane proteins [917], the G coupled receptors, including Nobel prizes in Medicine and Physiology: 1967 (studies of rhodopsin), 1988 (discovery of β-blockers), 1994 (discovery of G-protein), 2004 (odorant receptors), and even a Nobel prize in Chemistry: 2012 (3D structure of GPCRs) (GPCR) [918,919,920,921,922]

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It helps to maintain the skin’s natural moisture levels, preventing dryness and keeping the skin soft and supple