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Damaged mitochondria slow down and make less energy, reducing the efficacy and efficiency of bodily functions
respiratory
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It was observed that β -Arr mutants deficient in clathrin binding are still able to target the β 2 -AR to clathrin-coated pits, whereas β -Arr mutants lacking the AP-2 binding site can still interact with receptors, but the receptor- β -Arr complexes are essentially excluded from pits
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