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1032 Neurology Late Diagnosis of MELAS Can Lead to A Serious Brain Edema that Ultimately Requires Decompressive Craniectomy Oznur Gokce Nizam 1 , Esma Sengenc 2 , Osman Yesilbas 3 , Seyma Sonmez Sahin 2 , Akin Iscan 2 , Dilara Fusun Icagasioglu 2 1 Department of Pediatrics, Besmialem Vakif University, Turkey 2 Department of Pediatrics, Division of Pediatric Neurology, Bezmialem Vakif Univsersity, Turkey 3 Department of Pediatrics, Division of Pediatric Intensive Care, Bezmialem Vakif University, Turkey Background: Mitochondrial myopathy, encephalopathy, lactic acidosis and recurrent stroke-like episodes (MELAS) is a rare, maternally inherited, neurodegenerative disease caused by mutations in the mitochondrial DNA
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