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Moreover, and by using immunohistochemical analyses, abnormalities in nAChR were observed in several brain regions (e.g., neocortex, cerebellum, thalamus and striatum) of ASD patients, specifically with the major abnormalities being reduction in nAChR subunits and muscarinic receptors (M1 type) (Mukaetova-Ladinska, 2017)
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