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PAM contains two enzymatic domains—the peptidylglycine α -hydroxylating monooxygenase (PHM) domain and the peptidyl- α -hydroxyglycine α -amidating lyase (PAL) domain, which act sequentially to produce an amidated peptide

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These maps “proved to be hugely valuable to us and a significant step up in look development than what we’d done on prior projects,” he says