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Melatonin as an antioxidant, among other actions, directly neutralizes free radicals and ROS, stimulates the synthesis of antioxidant substances such as nitric oxide and glutathione, increases the activity of antioxidant enzymes such as glutathione peroxidase, superoxide dismutase (SOD2) and catalase, inhibits the activity of oxidative enzymes, and protects the function of mitochondria by increasing the activity of the transport chain and preventing depolarization of the mitochondrial membrane [30,33]

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and Tamar Weiss Prize Date: May 10, 1987 Event: Location: Dickinson College Douglas Michael Tuckman Emil R