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In the case of decorin and lumican, the defect in fibrillogenesis is accompanied by clinically apparent skin hyperextensibility and a striking reduction in skin tensile strength
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Single nucleotide polymorphisms & Gene Ontology (SNPs&GO) and predictors of human deleterious single nucleotide polymorphisms (PhD-SNPs) are both support vector machine (SVM)-based tools used to predict evolutionary information, protein sequences and functions if the given mutation can be classified as disease related
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