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🔥 AOD-9604 gets talked about like a “fat-melting miracle”… but what did the actual clinical trials show? Across 925 patients and 6 human studies, researchers dug deep into its effects, and the

That inconsistency, plus the failed 24-week endpoint, is why the obesity program closed before any larger confirmatory trial

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Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone