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In RBCs, peroxiredoxin 2 (Prx 2, PRDX2 ) is the most abundant isoform, and also plays a protective role by binding to and stabilizing hemoglobin [72,73]

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The chapter aims to elucidate biological sex-specific factors across all pharmacokinetic (PK) phases, subsequent therapeutic efficacy, and adverse drug reactions (ADRs), and to highlight implications for individualized therapy including within-woman variation across the menstrual cycle and other hormonal states

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