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The third factor is methyl binding domain proteins (MBDs), acting as readers, which recognize and bind to methylated CpG and translate their modifications via interacting with other proteins such as transcription factors and splicing-related proteins [12]

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We chose this exercise because previously it was used to separate intra- versus extra-cerebral signals 37 meaning that, potentially, VM induces changes in hemodynamics which are different for later time gates compared to the earlier ones