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Finally, we determined that METH self-administration modified dopamine cell firing rate to reach a new level of basal activity characterized by a higher number of spontaneously active neurons, albeit at lower firing and with decreased burst activity

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The inability to maintain reduced glutathione in erythrocytes leads to increased accumulation of peroxides, predominantly H 2 O 2 , that in turn results in a weakening of the cell wall and concomitant hemolysis