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The R groups that can be protonated/deprotonated include Lys, Arg, and His, which have a + 1 charge when protonated, and Glu and Asp (carboxylic acids), Tyr and Ser (alcohols), and Cys (thiol), which have zero charges when protonated
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[DOI] [PubMed] [Google Scholar] 58.Wang TH, Xiong LL, Yang SF, You C, Xia QJ, Xu Y, et al
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