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For bulk RNA-Seq analysis, renal TECs were FACS-sorted from kidney tissue of mice treated with glutamine or saline after IRI induction, based upon the expression of CD45 – Prominin-1 + (clone: MB9-3GB, Miltenyi Biotec, 130-102.197)
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Thus, the impairment of GSH uptake by mitochondria may be important to sensitize invasive cancer cells to prooxidant compounds capable of activating the cell death mechanism
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