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A 2021 review in Biomedical Research International (Liu et al.) confirmed that NNMT overexpression in adipose tissue directly impairs fasting blood glucose regulation
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The people who tend to benefit most include: Adults with diagnosed or suspected vitamin B12 deficiency Those following restrictive diets (vegan, vegetarian) that limit B12 food sources People with gastrointestinal conditions that affect nutrient absorption Adults over 60 who are at higher risk for marginal B12 status Individuals actively working on weight loss alongside diet and exercise Health-conscious professionals who want metabolic support during busy seasons If you’re unsure whether you’re a good fit, the best first step is a conversation with a qualified provider
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