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4.1.4 Targeting the JAK/STAT signaling pathway The JAK/STAT pathway, controlled by various inflammatory and growth factors, is important to immune-inflammatory responses

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Moreover, thioredoxin promoted the stemness of hepatocellular carcinoma cells by interacting with BACH1, stabilizing BACH1 expression by inhibiting its ubiquitination, and facilitated hepatocellular carcinoma metastasis both in vitro and in vivo