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The main sections of this manuscript examine the role of OS in cardiovascular, respiratory, oncologic, gastrointestinal, hepatobiliary, endocrine, hematologic, infectious, parasitic, neurologic, renal, dermatologic, ophthalmologic, orthopedic, reproductive, dental, and other canine diseases (Table 2)
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One of the “holy grails” in opioid pharmacology research has been to identify pathway-specific opiate receptor agonists that could activate antinociceptive signaling, without causing μ agonist-mediated euphorigenic responses, or kappa agonist-mediated dysphoria (2
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